ObjectivesMethods and Outcomes= 0. CAD after adjusting for traditional CAD factors ObjectivesMethods and Outcomes= 0. CAD after adjusting for traditional CAD factors

Bowen’s disease is a kind of squamous cell carcinoma in situ of the skin. disease, some specific dermatoscopic patterns were found, such as grayish-brown spots in linear arrangement and glomerular vessels. Like other pigmented lesions, pigmented Bowen’s disease may have various clinical and dermoscopic presentations. Widely observed patterns in this study were areas without structures (n = 25) and spots associated with areas without structures (n = 18). Furthermore, according to the histopathology, 17.3% of cases (n = 9) were associated with seborrheic keratosis.4 In our case, the blackened blotch and the area of bluish-gray veil made the lesion highly suspicious for melanoma associated or colliding with preexisting seborrheic keratosis. We also proposed the hypothesis that the blackened part of the lesion was a melanoacanthoma, which can also mimic melanoma.9 The term ‘melanoacanthoma’ denotes a rare and intensely pigmented variant of seborrheic keratosis. The term was used by Mishima and Pinkus in 1960 order A-769662 to make reference to a benign, pigmented lesion secondary to the proliferation of melanocytes and keratinocytes in the epidermal layers. Melanoacanthoma manifests as a slow-growing, generally solitary lesion on the mind, throat or trunk of the elderly, melanoma becoming its primary differential diagnosis.9 Collision tumors are seen as a the coexistence of two neoplasms at the same anatomical site, and their pathogenesis continues to be contentious. In such cases, prognosis and treatment are dictated by the tumor of higher intensity.10 Dermatoscopy can be an auxiliary tool in the analysis of pigmented lesions. In the event presented right here, the blackened part of the lesion demonstrated requirements suspicious for melanoma. It must be noted that people found no reviews in the literature of the atypical dermatoscopic demonstration of pigmented Bowen’s disease, making this case actually rarer. The histopathology, reference regular in cutaneous diagnoses, exposed the definitive analysis in this uncommon case of pigmented Bowen’s disease connected with seborrheic keratosis. Footnotes *Function carried out at order A-769662 the Instituto Nacional perform Malignancy, Rio de Janeiro (RJ), Brazil. Conflict of interest: non-e. Contributed by AUTHORS’CONTRIBUTIONS Karen de Almeida Pinto Fernandes0000-0002-2689-8248 Planning and composing of the manuscript Diana Carolina Salamanca Martinez 0000-0001-9058-2136 Style and preparing of the analysis Aretha Brito Nobre 0000-0002-7177-9838 Collecting, evaluation and interpretation of data Gabriella Campos-do-Carmo 0000-0003-2258-5823 Intellectual participation in propaedeutic and/or therapeutic carry out of studied instances REFERENCES 1. Mota AN, Pi?eiro-Maceira J, Alves Mde F, Tarazona MJ. Pigmented Bowen’s disease. An Bras Dermatol. 2014;89:825C827. [PMC free content] [PubMed] [Google Scholar] 2. Neubert T, Lehmann P. Bowens disease-a overview of newer order A-769662 treatment plans. Ther Clin Risk Manag. 2008;4:1085C1095. [PMC free content] [PubMed] [Google Scholar] 3. Lee JW, Hur J, Yeo KY, Yu HJ, Kim JS. A case of pigmented Bowens disease. GADD45A Ann Dermatol. 2009;21:249C251. [Google Scholar] 4. Cameron A, Rosendahl C, Tschandl P, Riedl Electronic, Kittler H. Dermatoscopy of pigmented Bowens disease. J Am Acad Dermatol. 2010;62:597C604. [PubMed] [Google Scholar] 5. Krishnan R, Lewis A, Orengo IF, Rosen T. Pigmented Bowens disease (squamous cellular carcinoma in situ): a mimic of malignant melanoma. Dermatol Surg. 2001;27:673C674. [PubMed] [Google Scholar] 6. Hernndez-Gil J, Fernndez-Pugnaire MA, Serrano-Falcn C, Serrano-Ortega S. Clinical and dermoscopic top features of pigmented Bowen disease. Actas Dermosifiliogr. 2008;99:419C420. [PubMed] [Google Scholar] 7. Firooz A, Farsi N, Rashighi-Firoozabadi M, Gorouhi F. Pigmented Bowens disease of the finger mimicking malignant melanoma. Arch Iran Med. 2007;10:255C257. [PubMed] [Google Scholar] 8. Namiki T, Ichiyama S, Funasaka Y, Ito M, Kanzaki A, Miura K, Nojima K, Saeki H, Yokozeki H, Tanaka M. Dermoscopy of pigmented papillated Bowen disease: A written report of two.

Leave a Reply

Your email address will not be published. Required fields are marked *